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Matrushri
Fertility Centers Consultancy (Agencies)
📞
+91 92473 51372 (Hyderabad)
📞
+91 81258 17240 (Tirupati)
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Infertility Treatment
🌸 Female Infertility 💙 Male Infertility 🧫 IVF – In Vitro Fertilisation 🔬 IUI – Intrauterine Insemination 🧬 ICSI ⚗️ PICSI 🫧 Blastocyst Culture 🧩 Genetics Program (PGT/PGS) ❄️ Fertility Preservation
Diagnostic Tests — Male
🧬 Semen Analysis 🔬 DNA Fragmentation Test 🧪 Hormone Profile 🩺 Testicular Biopsy 🫧 Anti-Sperm Antibody Test
Diagnostic Tests — Female
💉 AMH Test 🩺 HSG Test 🔬 Hormonal Panel 🫃 Pelvic Ultrasound
Calculators
📅 Period Calculator 🤰 Pregnancy Due Date Calculator 🧫 IVF Due Date Calculator
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ℹ️ About Us
Our Locations
📍 Hyderabad Clinic 📍 Tirupati Clinic
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🌸 Expert Female Fertility Care

Best Female Infertility
Treatment Centre

Compassionate, evidence-based care for all causes of female infertility — PCOS, endometriosis, blocked tubes, low ovarian reserve & more. Personalised plans, world-class technology.

40%
Infertility cases are
female-factor
25%
Cases caused by
ovulatory disorders
90%+
Treatable with right
diagnosis & care
Female fertility consultation
🏆
No.1 Fertility Centre AP & Telangana
22+
Fertility Specialists
11
Clinics across AP & TS
10,000+
Successful Pregnancies
Class 1000
IVF Laboratory
Understanding Female Infertility

What is Female Infertility?

Female infertility is defined as the inability to conceive after 12 months of regular, unprotected intercourse (or 6 months if the woman is over 35). It affects approximately 1 in 6 couples worldwide and accounts for about 40% of all infertility cases.

The causes are diverse — from ovulation disorders and blocked fallopian tubes to endometriosis, uterine abnormalities, hormonal imbalances, and age-related decline in egg quality and quantity. Many women have no obvious symptoms, making specialist evaluation essential.

At Matrushri, our gynaecologists and reproductive endocrinologists perform a comprehensive assessment to identify the exact cause and design a personalised treatment plan that maximises your chances of a healthy pregnancy.

🩺 Comprehensive Evaluation
💉 Hormonal Testing
🔬 AMH & Ovarian Reserve
🫃 Pelvic Ultrasound
🧬 Genetic Screening
🤝 Couple Counselling
Female fertility doctor
Root Causes

Common Causes of Female Infertility

Identifying the precise cause is the foundation of effective treatment. Our specialists evaluate every possible factor.

🔄

Ovulation Disorders

The most common cause — accounting for 25% of cases. PCOS, hyperprolactinaemia, thyroid disorders, and premature ovarian failure all disrupt normal ovulation.

Most Common
🌸

PCOS (Polycystic Ovary Syndrome)

Hormonal imbalance causing irregular periods, excess androgens, and multiple small ovarian cysts. The leading cause of anovulatory infertility in India.

Very Common
🫀

Endometriosis

Tissue similar to the uterine lining grows outside the uterus, causing inflammation, scarring, and distortion of pelvic anatomy. Affects 1 in 10 women of reproductive age.

10% of Women
🔗

Blocked Fallopian Tubes

Obstructions prevent sperm from reaching the egg and embryo from reaching the uterus. Often caused by PID, previous infections, or endometriosis.

Structural
🏠

Uterine Abnormalities

Fibroids, polyps, adhesions (Asherman's syndrome), or congenital uterine malformations can interfere with implantation and early pregnancy.

Structural
📉

Low Ovarian Reserve (DOR)

Reduced quantity or quality of eggs, often age-related but also caused by genetics, prior surgery, or chemotherapy. Diagnosed via AMH and antral follicle count.

Age-Related
⚗️

Hormonal Imbalances

Thyroid dysfunction, hyperprolactinaemia, adrenal disorders, and abnormal FSH/LH ratios can all disrupt the hormonal cascade needed for ovulation.

Hormonal
🧬

Genetic Factors

Turner syndrome, Fragile X premutation, chromosomal translocations, and other genetic conditions can affect egg quality, ovarian function, and implantation.

Genetic

Unexplained Infertility

In 10–15% of cases, all standard tests appear normal. Advanced testing for subtle immune, genetic, or endometrial factors may reveal the underlying cause.

10–15% of Cases
Warning Signs

Symptoms of Female Infertility

Many women with infertility have no symptoms beyond difficulty conceiving. These warning signs warrant a specialist evaluation:

📅

Irregular or Absent Periods

Cycles shorter than 21 days, longer than 35 days, or completely absent often indicate an ovulation disorder such as PCOS or hypothalamic dysfunction.

😣

Painful or Heavy Periods

Severe menstrual cramps, very heavy bleeding, or pain during intercourse (dyspareunia) may indicate endometriosis or uterine fibroids.

🌡️

Pelvic Pain

Chronic lower abdominal or pelvic pain — especially around ovulation or menstruation — can signal endometriosis, pelvic inflammatory disease, or ovarian cysts.

⚖️

Unexplained Weight Changes

Sudden weight gain or difficulty losing weight alongside irregular periods may indicate PCOS or thyroid dysfunction, both of which affect fertility.

💔

Recurrent Miscarriages

Two or more consecutive pregnancy losses indicate an underlying issue — chromosomal, uterine, immune, or hormonal — that requires specialist investigation.

🌿

Hormonal Symptoms

Excess facial hair (hirsutism), acne, hair loss, or milky nipple discharge (galactorrhoea) suggest hormonal imbalances affecting ovulation and fertility.

🔥

Hot Flashes Before Age 40

Vasomotor symptoms in younger women may indicate premature ovarian insufficiency (POI) or diminished ovarian reserve, requiring urgent fertility evaluation.

📆

Unable to Conceive After 12 Months

The primary indicator. If you are under 35 and have been trying for 12 months, or over 35 and trying for 6 months, consult a fertility specialist without delay.

How We Diagnose

Our Diagnostic Process

A thorough, step-by-step evaluation ensures we identify every factor affecting your fertility — nothing is left to chance.

1

Consultation & History

Detailed review of menstrual history, past pregnancies, surgeries, medications, lifestyle, and family history of fertility conditions.

2

Hormonal Blood Tests

FSH, LH, estradiol, progesterone, AMH, prolactin, thyroid (TSH, T3, T4), testosterone, and insulin levels assessed on specific cycle days.

3

AMH & Ovarian Reserve

Anti-Müllerian Hormone test and transvaginal antral follicle count (AFC) to assess the quantity and quality of remaining eggs.

4

Pelvic Ultrasound

Transvaginal ultrasound to evaluate uterine structure, endometrial lining, ovarian volume, follicle count, fibroids, polyps, and cysts.

5

HSG (Hysterosalpingography)

X-ray dye test to assess fallopian tube patency and uterine cavity shape. Detects blockages, adhesions, and structural abnormalities.

6

Laparoscopy

Minimally invasive surgical camera examination of the pelvic organs — the gold standard for diagnosing endometriosis and pelvic adhesions.

7

Hysteroscopy

Camera examination inside the uterine cavity to detect and treat polyps, fibroids, adhesions (Asherman's), and septum — often done alongside treatment.

8

Genetic Testing

Karyotype analysis, Fragile X premutation screening, and preimplantation genetic testing (PGT) to identify chromosomal causes of infertility or recurrent loss.

Conditions We Treat

Female Infertility Conditions

Our specialists are experts in diagnosing and treating every condition that affects female fertility.

PCOS — Polycystic Ovary Syndrome

PCOS is the leading cause of anovulatory infertility in India, affecting 1 in 5 women of reproductive age. It causes hormonal imbalance, irregular or absent ovulation, and multiple small follicles on the ovaries.

At Matrushri, we offer a comprehensive, individualised approach combining lifestyle intervention, medication, and ART when needed.

  • Lifestyle modification — diet, exercise, weight management
  • Ovulation induction with clomiphene citrate or letrozole
  • Metformin for insulin resistance management
  • Gonadotropin injections for controlled ovarian stimulation
  • Laparoscopic ovarian drilling (LOD) when medication fails
  • IVF with tailored stimulation protocols to prevent OHSS
Treatment Highlight

Personalised PCOS Protocols

Every PCOS patient is different. Our endocrinologists design bespoke stimulation protocols — carefully titrating doses to maximise egg yield while minimising ovarian hyperstimulation syndrome (OHSS) risk.

Ovulation Induction IVF Ready OHSS Safe

Endometriosis

Endometriosis affects up to 50% of women investigated for infertility. Endometrial-like tissue outside the uterus causes chronic inflammation, scarring, and distortion of pelvic anatomy that impairs fertility.

  • Laparoscopic excision of endometriotic lesions and adhesions
  • Cystectomy for endometriomas (chocolate cysts)
  • Medical suppression with GnRH analogues pre/post-surgery
  • IVF — bypasses tubal and pelvic factors
  • Fertility preservation before extensive surgery
  • Personalised IVF protocols for reduced ovarian reserve
Surgical Expertise

Advanced Laparoscopic Surgery

Our surgeons are trained in advanced endometriosis excision techniques, removing lesions thoroughly while preserving ovarian tissue and maximising post-surgical fertility.

Laparoscopic Surgery Tissue Preserving IVF Post-Op

Blocked Fallopian Tubes

Tubal blockage prevents fertilisation and is one of the most common structural causes of female infertility. HSG and laparoscopy confirm the location and extent of blockage.

  • Tubal cannulation for proximal (near-uterus) blockages
  • Laparoscopic salpingostomy for distal blockages
  • Salpingectomy for hydrosalpinx (fluid-filled tube) before IVF
  • IVF — most effective when tubes are irreparably damaged
  • Antibiotic treatment if infection is the underlying cause
  • Anti-TB treatment for genital tuberculosis-related blockage
Precision Diagnosis

HSG + Laparoscopy

We combine HSG for initial assessment with diagnostic laparoscopy for definitive diagnosis and simultaneous treatment, minimising the time to intervention and maximising your chances of natural conception.

HSG Diagnosis Laparoscopy IVF Option

Low Ovarian Reserve (DOR)

Diminished ovarian reserve means fewer eggs of lower quality, reducing the chances of natural conception. Age is the most common cause, but genetics, surgery, and prior chemotherapy also play a role.

  • AMH and AFC assessment to quantify reserve
  • Aggressive IVF stimulation protocols to maximise egg retrieval
  • Natural cycle or mini-IVF for gentle stimulation
  • Egg accumulation across multiple cycles (banking)
  • Fertility preservation (egg freezing) to arrest further decline
  • Donor egg IVF when reserve is critically low
Tailored IVF

Maximising Egg Yield

Our reproductive endocrinologists design aggressive yet safe stimulation protocols for poor responders, with close monitoring to retrieve every available egg and optimise the chances of a successful pregnancy.

Egg Banking Donor Option Close Monitoring

Uterine Abnormalities

Fibroids, endometrial polyps, intrauterine adhesions (Asherman's syndrome), and congenital uterine septum can all prevent implantation or cause recurrent pregnancy loss.

  • Hysteroscopic polypectomy — removal of uterine polyps
  • Hysteroscopic myomectomy — removal of submucous fibroids
  • Hysteroscopic adhesiolysis for Asherman's syndrome
  • Hysteroscopic metroplasty for uterine septum
  • Laparoscopic myomectomy for intramural or subserosal fibroids
  • Endometrial receptivity testing before IVF embryo transfer
Minimally Invasive

Hysteroscopic Surgery

Most uterine abnormalities can be corrected through hysteroscopy — a camera inserted into the uterus, eliminating the need for external incisions, with rapid recovery and same-day discharge in most cases.

Hysteroscopy Day Procedure Fast Recovery

Recurrent Pregnancy Loss (RPL)

Two or more consecutive miscarriages affect approximately 1–2% of couples. A thorough investigation can identify a treatable cause in up to 50% of cases.

  • Karyotyping of both partners to detect chromosomal causes
  • Antiphospholipid syndrome (APS) screening and treatment
  • Uterine evaluation by hysteroscopy and 3D ultrasound
  • Thyroid and hormonal optimisation
  • Preimplantation Genetic Testing (PGT-A) with IVF
  • Immune therapy for unexplained RPL
Comprehensive Investigation

Finding the Root Cause

We leave no stone unturned — investigating chromosomal, uterine, immune, thrombophilic, and hormonal factors. Our RPL clinic provides dedicated support and a clear management plan for every couple.

PGT-A IVF Immune Testing Genetic Panel
How We Treat

Treatment Options for Female Infertility

From simple ovulation induction to advanced IVF — we offer the full spectrum of evidence-based treatments tailored to your diagnosis.

💊

Ovulation Induction

Oral medications (clomiphene, letrozole) or injectable gonadotropins stimulate the ovaries to produce and release one or more eggs — combined with timed intercourse or IUI.

Learn More →
🔬

IUI — Intrauterine Insemination

Washed, prepared sperm is placed directly into the uterus around the time of ovulation. A minimally invasive first-line ART option for mild infertility.

Learn More →
🧫

IVF — In Vitro Fertilisation

Eggs are retrieved after controlled ovarian stimulation and fertilised with sperm in our Class 1000 lab. Resulting embryos are transferred to the uterus after 3–5 days.

Learn More →
🧬

ICSI — Intracytoplasmic Sperm Injection

A single healthy sperm is injected directly into each egg — ideal when there is also a male factor component, or when standard IVF fertilisation has failed.

Learn More →
🔭

Laparoscopy & Hysteroscopy

Minimally invasive surgical procedures to diagnose and simultaneously treat endometriosis, fibroids, polyps, adhesions, and blocked tubes — often restoring natural fertility.

Learn More →
❄️

Fertility Preservation

Egg or embryo freezing (vitrification) for women wishing to delay pregnancy, or those facing cancer treatment. Preserves your options for the future.

Learn More →
🧩

PGT — Preimplantation Genetic Testing

Embryos created through IVF are tested for chromosomal abnormalities (PGT-A) or specific genetic conditions (PGT-M) before transfer, reducing miscarriage risk.

Learn More →
🤝

Donor Egg IVF

When a woman's own egg quality or quantity is insufficient, donor eggs from a screened, matched donor are fertilised and transferred — offering excellent success rates.

Learn More →
💉

Hormonal & Medical Therapy

Targeted hormone therapy for thyroid disorders, hyperprolactinaemia, luteal phase deficiency, and other hormonal causes — often restoring natural fertility without ART.

Learn More →
Your Fertility Journey

What to Expect at Matrushri

From your first call to a positive pregnancy test — here is how we guide you every step of the way.

1

Book a Free Consultation

Call us or fill the form below. Our patient coordinators will schedule your first appointment at the nearest Matrushri clinic — often within 24–48 hours.

2

Comprehensive Fertility Assessment

Our gynaecologist and reproductive endocrinologist conduct a full evaluation — medical history, hormonal tests, pelvic ultrasound, and review of any prior investigations.

3

Advanced Diagnostic Tests

Based on initial findings, we may recommend AMH, HSG, 3D ultrasound, laparoscopy, hysteroscopy, or genetic testing to pinpoint the exact cause.

4

Personalised Treatment Plan

Your specialist presents a clear, tailored treatment plan — explaining every option, success rates, timelines, and costs. You make the decision together.

5

Treatment & Close Monitoring

Whether ovulation induction, surgery, or IVF — you receive dedicated monitoring with regular ultrasounds, blood tests, and direct access to your care team throughout.

6

Pregnancy Confirmation & Beyond

A positive pregnancy test is just the beginning. We provide early pregnancy scans, ongoing support, and a warm handover to your obstetric team for a safe, healthy pregnancy.

Why Matrushri

Why Women Choose Matrushri

We combine clinical excellence with genuine compassion — because every woman's journey deserves both.

👩‍⚕️

Expert Women's Health Team

Dedicated gynaecologists, reproductive endocrinologists, embryologists, and counsellors — all experienced in female infertility and committed to personalised care.

🔬

Class 1000 IVF Laboratory

Our internationally certified clean-room IVF lab maintains optimal conditions for egg retrieval, fertilisation, ICSI, embryo culture, and cryopreservation.

🏥

All Treatments Under One Roof

From ovulation induction and laparoscopy to IVF, PGT, donor eggs, and fertility preservation — complete female fertility care without referrals elsewhere.

📋

Truly Personalised Plans

No protocols are ever copy-pasted. Every plan is designed individually after thorough evaluation, with shared decision-making and clear explanation of every step.

💬

Emotional & Psychological Support

Fertility treatment is emotionally demanding. Our counsellors provide dedicated psychological support throughout your journey — because mental wellbeing matters.

📍

11 Clinics Across AP & Telangana

With centres in Vijayawada, Hyderabad, Secunderabad, Guntur, Karimnagar, Rajahmundry, Warangal, and more — expert care is always close to home.

Real Stories

Success Stories

Real patients, real outcomes — thousands of women have trusted Matrushri on their path to motherhood.

★★★★★

"After 4 years of trying and 2 failed IVF cycles elsewhere, Matrushri diagnosed my endometriosis correctly for the first time. After laparoscopic surgery and one IVF cycle, I am now 8 weeks pregnant. I cannot thank this team enough."

★★★★★

"I was told by another clinic that donor eggs were my only option due to PCOS and low AMH. The doctors at Matrushri designed a gentle IVF protocol and retrieved 6 eggs. I am now a proud mother of twins!"

★★★★★

"Three miscarriages left us devastated. Matrushri found that I had a uterine septum and antiphospholipid syndrome. After hysteroscopic surgery and the right medications, our fourth pregnancy was successful."

Common Questions

Frequently Asked Questions

When should a woman see a fertility specialist?
If you are under 35 and have been trying to conceive for 12 months without success, see a specialist. If you are 35 or older, seek advice after 6 months. Women with irregular periods, PCOS, endometriosis, known uterine issues, or a history of miscarriage should seek evaluation sooner — even before trying to conceive.
Can PCOS affect my ability to get pregnant?
Yes — PCOS is the most common cause of anovulatory infertility. However, with appropriate treatment, the vast majority of women with PCOS can achieve pregnancy. Many respond well to ovulation induction with oral medications, and those who don't can proceed to IVF with excellent success rates.
What is the success rate of IVF at Matrushri?
Success rates vary based on age, diagnosis, and individual factors. Our Class 1000 IVF laboratory and experienced embryologists deliver above-average success rates. Women under 35 typically have the highest success rates per cycle. We will discuss realistic expectations specific to your case during consultation.
Is IVF painful? What does the process involve?
IVF involves daily injections for 10–14 days to stimulate the ovaries, followed by egg retrieval under sedation (virtually painless). Embryos develop in the lab for 3–5 days, then one or two are transferred to the uterus (a simple, pain-free procedure). Most women tolerate the process well and continue normal activities throughout.
Can endometriosis be cured?
Endometriosis cannot be permanently cured, but it can be effectively managed. Laparoscopic surgery to remove lesions and endometriomas significantly improves fertility and reduces pain. After surgery, many women conceive naturally. For those who don't, IVF offers excellent success rates. Suppressive hormonal therapy prevents recurrence after treatment.
Does age really affect female fertility?
Yes, significantly. A woman is born with all the eggs she will ever have. Egg quantity and quality decline with age — gradually in the 30s, more steeply after 35, and dramatically after 40. However, many women over 35 and 40 do conceive with the right treatment, and donor egg IVF offers excellent success rates for those with severely diminished reserve.
How much does female infertility treatment cost?
Costs vary widely depending on the treatment. Initial evaluation and hormonal tests are relatively affordable. Ovulation induction with IUI is less expensive than IVF. IVF costs depend on the protocol, number of cycles, and any additional procedures. We offer transparent pricing and EMI options — your patient coordinator will discuss all costs upfront, with no hidden charges.
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15,000+
IVF Pregnancies
👩‍⚕️
22+
Fertility Super Specialists
🏥
11
Clinics Across AP & Telangana
🏆
#1
Rated Fertility Chain in Region

Infertility Treatment Options

We offer the full spectrum of fertility treatments — from the simplest to the most advanced — customised to each couple's unique medical profile.

🌸
Female
Female Infertility
Personalised treatments to help women overcome fertility challenges using hormonal therapy, surgical interventions, and ART protocols tailored to root cause.
Hormonal Therapy Laparoscopy Ovulation Induction
Learn More
💙
Male
Male Infertility
Advanced andrological solutions to improve sperm count, motility, and morphology — boosting the chances of natural or assisted conception significantly.
Semen Analysis Sperm Retrieval DNA Fragmentation
Learn More
🔬
Assisted
IUI – Intrauterine Insemination
A simple, minimally invasive procedure where washed sperm is placed directly into the uterus to enhance the chance of fertilisation with expert timing.
Minimally Invasive Quick Procedure Cost-Effective
Learn More
🧫
Advanced
IVF – In Vitro Fertilisation
A guided journey to conception where eggs are fertilised in our Class 1000 IVF lab and the best embryo is transferred with cutting-edge precision technology.
Class 1000 Lab RI Witness System K-System Incubators
Learn More
🧬
Advanced
ICSI – Intracytoplasmic Sperm Injection
Precision-driven treatment for severe male infertility — a single healthy sperm is directly injected into an egg under high magnification for fertilisation.
Severe Male Infertility High Precision Best Outcomes
Learn More
⚗️
Advanced
PICSI – Physiological ICSI
Enhances embryo quality by selecting only the healthiest, most mature sperm using hyaluronan binding — reducing the risk of failed implantation.
Hyaluronan Binding Better Embryo Quality Fewer Miscarriages
Learn More
🫧
Embryology
Blastocyst Culture
Giving embryos the best start — culturing embryos to Day 5 blastocyst stage allows selection of the most viable embryo for transfer, boosting success rates.
Day 5 Culture Higher Success Better Selection
Learn More
🧩
Genetics
Genetics Program (PGT/PGS)
Ensuring healthier pregnancies through Preimplantation Genetic Testing — screening embryos for chromosomal abnormalities before transfer to the uterus.
PGT-A / PGT-M Chromosomal Screening Healthy Pregnancy
Learn More
❄️
Preservation
Fertility Preservation
A future-ready approach — egg, sperm, or embryo freezing (vitrification) safeguards your fertility for when the time is right, whether for medical or personal reasons.
Egg Freezing Sperm Banking Embryo Vitrification
Learn More

Infertility Diseases & Conditions

Our specialists diagnose and manage a wide range of conditions affecting female and male fertility with evidence-based, compassionate care.

🔄
PCOD / PCOS
Polycystic Ovary Syndrome is one of the most common causes of female infertility. We manage it with lifestyle, hormonal, and fertility treatments.
Explore Treatment →
🫀
Uterine Fibroids
Non-cancerous growths that can affect implantation and pregnancy. We offer minimally invasive surgery and medical management.
Explore Treatment →
🌺
Endometriosis
Tissue similar to the uterine lining growing outside — causing pain and infertility. Treated with laparoscopy and fertility protocols.
Explore Treatment →
🔗
Blocked Fallopian Tubes
Tubal blockage prevents egg from meeting sperm. We treat with selective salpingography, laparoscopy, or bypass via IVF.
Explore Treatment →
⚖️
Hormonal Imbalance
Thyroid, prolactin, FSH/LH irregularities disrupting ovulation and fertility — diagnosed and corrected with precision hormonal therapy.
Explore Treatment →
🐣
Low Ovarian Reserve
Low AMH or poor egg quality requires specialised stimulation protocols. We tailor treatment to maximise your egg yield and embryo quality.
Explore Treatment →
🔬
Low Sperm Count / Azoospermia
Severe male factor infertility addressed with TESA, PESA, micro-TESE sperm retrieval combined with ICSI for fertilisation.
Explore Treatment →
💔
Recurrent Pregnancy Loss
Three or more miscarriages investigated for genetic, anatomical, hormonal, or immunological causes — with targeted interventions.
Explore Treatment →